MyBioSource.com's PANX1 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The PANX1 Antibody was generated using Pannexin 1, and PANX1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Function: Structural component of the gap junctions and the hemichannels. May play a role as a Ca2+-leak channel to regulate ER Ca2+ homeostasis.
Subunit Structure: Homohexamer. Forms homomeric or PANX1/PANX2-heteromeric intercellular channels on coexpression in paired Xenopus oocytes (By similarity).
Post-translational Modifications: S-nitrosylation inhibits channel currents and ATP release.
Similarity: Belongs to the pannexin family